fenben for humans is an anthelmintic drug used to treat parasites and worms in animals. It has also been shown to have antitumor effects in laboratory tests. However, there is no evidence that it can cure cancer in humans.
The claim was made by Joe Tippens, who claims that he used fenben to cure his cancer. The claims have spread to other websites and social media.
It is a benzimidazole
Fenbendazole is a broad-spectrum anthelmintic drug used to treat parasitic worms in humans and animals. It is also a powerful compound that has the potential to be repurposed as an anti-cancer drug. It works by binding to b-tubulin microtubules and disrupting their polymerization. In this way, it can prevent cells from replicating themselves. Moreover, it can interfere with glucose uptake. This can reduce glycogen stores and limit ATP formation in cancer cells.
It is important to note that there isn’t sufficient evidence that fenbendazole can cure cancer in humans. Its effectiveness is based on anecdotal evidence, and it hasn’t gone through clinical trials. However, it does slow down the growth of cancer cells in cell cultures and animals. It may be a good treatment option for people with gastrointestinal issues or liver disease, as it is highly effective at treating parasitic infections.
The claim that fenbendazole can help cure cancer spread after Joe Tippens, a US man diagnosed with late-stage lung cancer, claimed that the drug was responsible for his remission. However, it’s important to note that Tippens was enrolled in a clinical trial of another anti-cancer drug at the time he made his claims. This means that other factors, including conventional cancer treatments, weren’t accounted for. Regardless, his anecdotal experience still gained significant traction online and caused a shortage of the drug in South Korea.
It interacts with tubulin
The benzimidazole carbamate drug fenbendazole interacts with tubulin, an important component of microtubules. This interaction disrupts the cell cycle and kills parasites. The fenbendazole is used as an anthelmintic and also has anticancer properties. It also inhibits the proliferation of human cancer cells by depolymerizing MTs. In addition, fenbendazole decreases glucose uptake in cancer cells, which prevents them from obtaining the energy they need to grow.
In a study of two types of human cancer cells, researchers found that fenbendazole reduced the growth rate of the H460 and A549 cell lines by interfering with the formation of microtubules. Microtubules are a fundamental cellular structure that are involved in many vital functions, including the cell cycle and mitosis. During the cell cycle, chromosomes are lined up at metaphase and divided evenly during anaphase by the help of the mitotic spindle, which is formed from microtubules. The research team investigated whether fenbendazole can interfere with the formation of microtubules and inhibit cell division by blocking their assembly.
The Joe Tippens protocol, or the “Joe Tippens diet,” is a treatment plan that includes fenbendazole and vitamin supplements. The protocol grew in popularity after a man with stage 4 cancer claimed to have been cured by the drug, which is sold under the brand name Panacur. However, the anecdotal evidence is limited and there are no scientific studies that prove fenbendazole’s efficacy against cancer.
It is a broad-spectrum anthelmintic
Fenbendazole (FZ) is a benzimidazole carbamate with broad-spectrum antiparasitic activity. It acts by binding to b-tubulin microtubule subunits and disrupting their polymerization. This causes detachment of host parasites and their death. It also inhibits glucose uptake by preventing the formation of glycogen stores, and it blocks ATP production in susceptible parasites. FZ is also a powerful antitumor agent, and it binds to the tubulin protein to promote the degradation of cancer cells.
Currently, anthelmintics are widely used as veterinary drugs to control intestinal parasites in animals and humans. These medications are very effective against many different species of worms. They have been in use for approximately 50 years and are a safe option to treat intestinal parasites. There are three main groups of anthelmintic drugs, including benzimidazole carbamates, probenzimidazoles, and imidazothiazoles. Each group has its own mode of action, so it is important to choose the right anthelmintic for your animal’s needs.
While anthelmintics may cure cancer in animals, they are not considered to be cures for human cancer. Nevertheless, fenbendazole is a popular treatment for cancer patients and has been shown to have anticancer effects in a number of cases. A recent study found that fenbendazole can inhibit tumor growth, although the results were not conclusive. However, anecdotal evidence suggests that fenbendazole can help with a variety of other conditions.
It is a chemotherapeutic agent
The repurposing of anthelminthic pleiotropic benzimidazole carbamate drugs like fenbendazole (FZ) for the treatment of cancer has opened new avenues. Currently, these drugs are used in veterinary medicine to treat parasitic worms such as Ascaris, hookworms, and a single species of tapeworm called Taenia pisiformis. However, this new use of the drug is controversial. This is partly because of the ease with which nonmedical individuals can disseminate information using social media. This has the potential to lead to the dissemination of unproven medical facts that could endanger the health of patients.
In the laboratory, fenbendazole has been shown to interfere with glucose uptake, which is necessary for cancer cell growth. This effect has been found in both human and animal models. Moreover, the drug has also been shown to decrease tumor growth in mice and inhibit the proliferation of human breast cancer cells.
It has not yet been tested in humans, though, so it is not known whether it will work in people. A specialist cancer information nurse at Cancer Research UK told Full Fact that there is insufficient evidence to suggest that fenbendazole cures cancer, and it has not gone through any clinical trials to find out if it is safe and effective. Despite this, the claim has spread to a wide audience and is being widely shared on social media.